THE CURRENT AND FUTURE OF THE PHARMACEUTICAL INDUSTRY CLUSTER

  1. CORE INDUSTRIES

Component

Patented Ethical Drugs (MNC)

Generic Ethical Drugs

Over-The-Counter Drugs (OTC) Patented & Generies

Traditional Medicines

Veterinary Pharmaceutical

C

U

R

R

E

N

T

Limited Contact Manufacture

For Examples:-

  • Analgesics
  • Antacids
  • Antihypertensives;
  • Antiashmatics;
  • Antibiotics/Antifungals; and
  • Diuretics

For Example:

  • Paracetamol;
  • Eye-Drops; and
  • Vitamins

For Example:

  • Sea-Cucumber Extract;
  • Herbal/ Health Tea;
  • Medicated Oils; and
  • Chinese Medicines
  • Animal Feed Supplements; and
  • Vaccine For New Castle Disease
 

Patented Ethical Drugs

Generic Ethical Drugs

Genetic Engineered Drugs Including Vaccines

Traditional Medicines

Blood Products

F

U

T

U

R

E

For Example:

  • Imigran;
  • Grisorin;
  • Neurological Drugs;
  • Clozaril (Clozapine);
  • Naltrexane; and
  • Obesity Drugs

For Example:

  • Analgesics;
  • Antacids;
  • Antihypertensive;
  • Antiasthmatic
  • Antibiotics/ Antifungals;
  • Anticonvulsant; and
  • Anti-Cancer
  • Hepatitis B Vaccine, and
  • Recombinant Proteins (Insulin)

 
  • Same as current; and
  • New Medicines Based On Malaysian Rich Fauna & Flora & Active Research
  • Plasma Fractionation;
  • -F V111;
  • -F 1X; and
  • -Albumin

 

 

Veterinary Pharmaceutical

Medical Diagnostics

Active Ingredients
  • Same As Current Amnd Expanded List;
  • Possible Production Of Active Ingredients (Oxytetracyline, Tylosin, Salinomycin, Ivermectin, Riboflavin). By Fermentation Using Palm Oils As Feedstock
  • Biosensor;
  • Elisa-Based;
  • DNA-Based;
  • Immunological-Based (Monoclonal Antibody); and
  • Chemical And Physical-Based

For Example:

  • Cephalalosporin C; and
  • Cytokines

 

Source: Second Industrial Masterplan (IMP2)

 

 

 

 

 

  1. KEY SUPPLIER

 

Current

Specialised Pharmaceutical

Production Machinery (Imported)

Packaging For Pharmaceutical
 
  • Clean Room
  • Paper
  • Aluminum Foils;
  • Glass
  • Gelatine;
  • PVC Films, and
  • Plastic Containers

FUTURE

Specialised Pharmaceutical

Production Machinery Imported & Locally Fabricted

Packaging
 
  • Clean Room; and
  • Pharmaceuticals Equipment
  • Expanded Packaging Materials

 

Source: Second Industrial Masterplan (IMP2)

 

 

  1. ECONOMIC FOUNDATION (cont. Table 4.1)

 

Technology

  

Human Resources

Finance
  • SIRIM-Biotechnology. Chemical Technology & Engineering;
  • FRIM-Plant-Biodiversity;
  • MINT-Nuclear Medicine
  • IMR-Medical Biotechnology Clinical Research;
  • PORIM-Biotechnology Veterinary Science;
  • USM-Pharmacy;
  • UKM-Pharmacy;
  • UM-Chemistry, Microbiology, Biotechnology, Pharmacy With Emphasis On Industrial Pharmacy; and
  • UTM Chemical Engineering

Current

  • Universities;
  • National Pharmaceutical Bureau (Min. Of Health); and
  • Drug Control Authority

 
  • Local Financing and
  • FDI

 

Technology

FUTURE

Human Resources

Finance
  • Imported;
  • Local Through Indigenous R&D, Discovery & Development Of New Drugs; and
  • Production Of Active Ingredients.
  
  • Universities;
  • National Pharmaceutical Bureau (Min. Of Health); and
  • In-house Training Firms
  • Local Financing:
  • FDI and
  • Venture Capital

Source: Second Industrial Masterplan (IMP2)

MALAYSIA: EXPORT, IMPORT AND DEFICIT IN PHARMACEUTICALS (SITC 540) (RM ‘ 000)

ITEM

 1988 1989 1990 1991 1992 1993   1994

1995

Export
SITC 541 2,151 22,520  29,422 33,652 2,409 30,698  41,592

59,284
SITC 541 33,070 38,227 40,217 46,729  52,092 49,507  63,780

74,787
Total 35,221 60,747 69,639 80,381 54,501 80,205 105,372

134,071

Imports

SITC 541 

68,526 72,657 79,891 81,945 81,713 82,454 91,943 119,814
SITC 542 17,477 228,399 232,856 273,681 345,141 283,700 328,780

412,381
Total 86,003 301,056 312,747

355,626

426,854 366,154  420,723 532,195

Balance of Trade
SITC 541 -66,375 -50,137 -50,469 -48,293 -79,304 -51,756 -50,351

-60,530
SITC 542 15,593 -190,172 -192,639 -226,952 -293,49 -234,193 -265,000

-337,594
Total -50,782 -240,309 -243,108 -275,245 -372,353 -285,949 -315,351 -398,124

 

Source: Department of Statistic, Malaysia

Note : SITC541 : Medicinal and Pharmaceutical Products

: SITC542 : Medicaments (including Veterinary Medicaments)

In IDS Project Report : Biotechnology Application in Sabah, April 1998